Noopept is considered non-toxic and safe — however, like any other pharmacologically-active substance, it comes with a few side-effects when taken in high doses.
As long as you remain within the recommended dosage of 10 to 40 mg per day, you’re unlikely to experience any major side-effects.

Side Effects of Noopept Include

  • Fatigue
  • Headaches
  • Insomnia or sleep disruptions
  • Digestive upset (diarrhea or bloating)
The most common side effects of Noopept is insomnia and headaches.
Insomnia is a result of the stimulating nature of Noopept. While this nootropic is much less stimulating than caffeine, it can still make it difficult to fall asleep at night. The easiest way to avoid this effect is to take Noopept earlier in the day, at least 8 hours before your intended bedtime.
The second most common side-effect, headaches, is usually caused by a combination of dehydration and choline deficiencies caused by the effects of Noopept. To avoid this, make sure you drink plenty of water while using Noopept, and take a choline supplement (such as alpha-GPC) alongside the nootropic to avoid choline deficits.